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Male Infertility 男性不育

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  • 作者:万静
  • 更新日期:2012-09-12 16:16
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Azoospermia, oligospermia and asthenozoospermia can be divided into three categories: Low gonadotropin, high gonadotropin and blocking. Without clear diagnosis, any blinded treatment is wrong, including artificial insemination. For clear diagnosis,

Azoospermia, oligospermia and asthenozoospermia can be divided into three categories: Low gonadotropin, high gonadotropin and blocking. Without clear diagnosis, any blinded treatment is wrong, including artificial insemination. For clear diagnosis, electrochemiluminescence, pituitary stimulation test, testicular B-testicular endocrine analysis etc., shall be conducted. Beijing Antai OBGYN hospital newly introduced Proxeed®, which shows wonderful efficacy for the treatment of oligospermia and asthenozoospermia caused by non-testicular factors.

{0>男性不育定义<}70{>Definition of Male Infertility

男性不育
男性不育
 

Male infertility is a disease caused by male factors. Generally, for cohabitated couples, if the man can not get the women pregnant within one year under no artificial contraceptive measure, the man is diagnosed as male infertility.

Symptoms of Male Infertility

Male infertility symptoms include varicocele, testicular atrophy, small penis, low libido, premature ejaculation and impotence, etc.; some patients showed no symptoms.

Examinations for Male Infertility

vulvar colposcopy + electrochemical luminescence immunoassay hormones detection + dynamic digitization contrast + four-dimensional ultrasound + sperm smear + full test of semen + the andrology examination.

Antai Treatment for Male Infertility

Azoospermia, oligospermia and asthenozoospermia

Azoospermia, oligospermia and asthenozoospermia can be divided into three categories: Low gonadotropin, high gonadotropin and blocking. Low gonadotropin is caued by hypothalamus and pituitary dysfunction; high gonadotropin is caued by testicle failure and castration and blocking is caused by Vas deferens obstruction and sterilization etc. Without clear diagnosis, any treatment is blinded, including artificial insemination. For clear diagnosis, electrochemiluminescence, pituitary stimulation test, testicular B-testicular endocrine analysis etc., shall be conducted. Beijing Antai OBGYN hospital newly introduced Proxeed®, which shows wonderful efficacy for the treatment of oligospermia and asthenozoospermia caused by non-testicular factors.

Semen non-Liquefaction

Semen liquefaction is not a disease and does not result in infertility; it is a protective response by semen; once the semen enters the vagina or similar environment, it will will naturally liquefacte; so it will not lead to infertility. So there must be other reason for man who cannot get women pregnant. And artificial insemination with forced liquefied semen is probably not a wise choice.

Sperms present in the semen in which there is a lot of material that protects and nutralize the sperm. For man with non-liquefied semen, there is more and stronger protective substances, which is a good thing.

Male Infertility Etiology

1. Semen abnormalities: no sperm, less sperm, or weakened activity or morphological abnormalities.

2. Testicle abnormalities: there are three kinds of testicle abnormalities:

1) Cryptorchidism: unilateral cryptorchidism causes about 30% to 60% of the infertility, and the bilateral cryptorchidism causes about 50% to 100%. Besides infertility, it could also induce malignant lesion.

2) During fetal period, the embryo primordia was damaged due to adverse environmental factors; 3) early testicular damage could be caused by birth injury during childbirth process.

3. Acquired testicle injury: including hernia repair, hydrocele surgery, testicle fixation etc., that could damage testicle vascular and hinder blood supply that leads to testicular atrophy.

4. Sperm transport disruption: epididymis and vas deferens tuberculosis can block vas deferens and sperm transportation, cause impotence, premature ejaculation and other sexual dysfunction, which would stop sperm from entering woman's vagina.

5. Hydrocele: the hydrocele could compress testicle blood circulation and can lead to testicle infection or atrophy. The occurrence of the disease is 16-19% after puberty. 6. Endocrine factors: male endocrine is controlled by hypothalamus - pituitary - testicular axis; oligozoospermia and azoospermia caused by pituitary, thyroid and adrenaline dysfunction can lead to infertility.

7. Genetic factors: such as Klinefelter syndrome caused by sex chromosome abnormality, male Turner syndrome and other. 8. Immune factors: sperms are exposed in immune system; so when the sperm seminal plasma in the body produces antibodies against their own sperms, the ejected sperms will result in agglutination which will prevent women from getting pregnant.

9. Genital infection: infections by bacteria, viruses, protozoa etc., can directly damage the testicles and lead to testicular atrophy, testicular tuberculosis, destruction of testicular tissue, and can seriously affect spermatogenesis, reduce sperm activity and lead to infertility. For example, 20% of the mumps happened in early puberty would result in concurrent orchitis that causes infertility.

10. Infertility due to neurological dysfunction and neurological diseases: such as paraplegia, impotence.

11. Varicocele-induced infertility: varicocele can affect spermatogenesis and leads to infertility, which accounts for about 30% to 40% of male infertility.

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