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母婴溶血性流产的检查Screening for maternal and infant hemolytic miscarriage

  • 来源:xjat
  • 作者:xjat
  • 更新日期:2019-05-30 14:00
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陈凤林教授指出:母婴溶血需要检查孕妇及丈夫的血型。孕妇到妊娠第16周时查血清抗体,作为基础水平,至28~30周时再测抗体,以后每月测一次。如抗体效价上升,提示胎儿可能受累。在孕期28~31周时宜同时测定羊水胆红素和羊水卵磷脂(L)鞘磷脂(S)比值;如L/S2,

陈凤林教授指出:母婴溶血需要检查孕妇及丈夫的血型。孕妇到妊娠第16周时查血清抗体,作为基础水平,至28~30周时再测抗体,以后每月测一次。如抗体效价上升,提示胎儿可能受累。在孕期28~31周时宜同时测定羊水胆红素和羊水卵磷脂(L)鞘磷脂(S)比值;如L/S≥2,提示胎儿肺已成熟,有条件考虑提早分娩。

Professor Chenfenglin pointed out that maternal and infant hemolysis requires the examination of the blood type of the pregnant woman and her husband. The pregnant woman checks the serum antibody at the 16th week of pregnancy, as the basic level, and then measures the antibody at 28-30 weeks, and then tests it once a month. If the potency of the antibody increases, it suggests that the fetus may be affected. At 28 to 31 weeks of pregnancy, the ratio of amniotic bilirubin and amniotic lecithin(L) sphingolipid(S) should be determined simultaneously; Such as L/S ≥ 2, indicating that the fetal lung has matured, conditional consideration of early delivery.

对Rh阴性孕妇用PCR法检测羊水中胎儿RhD血型的基因,也可直接从孕妇静脉血中用荧光PCR法测出胎儿RhD的DNA,以确定胎儿的血型。

For Rh-negative pregnant women, the PCR method is used to detect the gene of the fetal RhD blood type in amniotic fluid, and the DNA of the fetus RhD can also be measured directly from the maternal vein blood using the fluorescent PCR method to determine the fetal blood type.

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