先天性卵巢发育不全/特纳氏综合征/45,XO Congenital ovarian hypoplasia / Turner's syndrome / 45, XO转载2008-02-26
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- 作者:cfl
- 更新日期:2019-07-04 13:49
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先天性卵巢发育不全又称特纳氏综合征,是一种先天性染色体异常所致的疾
先天性卵巢发育不全又称特纳氏综合征,是一种先天性染色体异常所致的疾病。染色体核型是45,XO,即缺少一条性染色体X,或46,XXP或46,XX q或其嵌合体,据此就可诊断为脱纳氏综合征。由于性染色体异常,卵巢不能生长和发育,因此卵巢呈条索状纤维组织,无原始卵泡,也没有卵子。
Congenital ovarian hypoplasia, also known as Turner's syndrome, is a disease caused by congenital chromosomal abnormalities. The chromosome karyotype is 45, XO, that is, the lack of a sex chromosome X, or 46, XXP or 46, XXq or its chimera, according to which it can be diagnosed as denar's syndrome. Due to abnormal sex chromosomes, the ovaries can not grow and develop, so the ovaries have a rosette fiber tissue, no original follicles, and no eggs.
临床特征为身材矮小,成年后身高极少超过150cm,颈部发际低,甚至可达肩部,颈项短而粗。半数以上颈部皮肤松弛,从耳后乳突部到肩峰,呈蹼颈,胸部宽,呈盾牌状,肘关节外翻,乳头外移,先天性主动脉狭窄,伴闭经和第二性征不发育,体内FSH增高,雌激素极度低落。
The clinical features are short stature, rarely more than 150cm in height after adulthood, low hairline in the neck, and even up to the shoulders. The neck is short and thick. More than half of the neck's skin is loose, from the posterior mastoid to the shoulder peak, with a webbed neck, a wide chest, a shield shape, an elbow roll, a nipple movement, congenital aortic stenosis, accompanied by amenorrhea and secondary sexual characteristics. Developmental, increase in body FSH, Estrogen is extremely low.
各种不同类型的嵌合型如45,XO/46,XX,45,XO/47,XXX等,这些嵌合型病例比45,XO型接近于正常女性。少数患者有时可有月经来潮,乳房发育,甚至受孕,但有较高的流产和死产率。
Various types of mosaics such as 45, XO/46, XX, 45, XO/47, XXX, etc., these mosaics are 45 and XO are close to normal women. A few patients may sometimes have menstrual cramps, breast development, and even pregnancy, but there is a high rate of miscarriage and stillbirth.
安太特色治疗
Antai special treatment
实践证明任何治疗,都不能促进卵巢发育,都不能使患者恢复生育功能。
Practice has proved that any treatment can not promote ovarian development and can not restore reproductive function to patients.
经过生长激素和雌孕雄激素的治疗,可以促进身高,刺激乳房及生殖器官发育。达到正常性生活的目的。
After the treatment of growth hormone and estrogen androgen, it can promote height and stimulate breast and reproductive organ development. Achieve the purpose of normal sexual life.
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