染色体46,XY,add(12)(q13) 能不能治疗?Chromosome 46, XY, add(12)(q13) can be treated?

46,XY,add(12)(q13)前面有流产过三次，都是自然流产，最后一次是试管婴儿成功后发生了胎停育，想问问，这种染色体还有得治吗?

46, XY, add(12)(q13) had three miscarriages in front of them, all of which were spontaneous miscarriages. The last one was that after the success of the test-tube baby, the pregnancy stopped. I want to ask if this chromosome can be treated?

陈凤林教授指出：染色体46,XY,add(12)(q13)属于携带性未知起源异常，不会影响到胎儿的生长发育，只会遗传，几次自然流产一定有其他原因，只是未确诊而已，染色体 46,XY,add(12)(q13)做试管婴儿是走弯路了，建议做正规检查治疗，目前有专利技术可以攻克习惯性流产。

Professor Chenfenglin pointed out: Chromosome 46, XY, add(12)(q13) is an anomaly of the unknown origin of carrying and will not affect the growth and development of the fetus. It will only be inherited. There must be other reasons for several spontaneous miscarriages, but it has not been diagnosed. Chromosome 46, XY, add(12)(q13) as a test-tube baby is a detour. It is recommended to do regular examination and treatment. There are currently patented technologies that can overcome habitual miscarriage.

其实夫妇染色体异常不会导致习惯性流产。原因是，染色体异常形成于精卵结合之初，染色体异常有三种情况：致死型异常;致残型异常;携带型异常。致死型，是染色体严重变异，结局是胚胎枯萎而自然流产，不会有出生婴儿。致残型,是染色体中度异常，多是染色体数量变化，如21三体，22三体，特纳综合征(多一条Y染色体)等出生的都是残疾人，基本都无生育能力。携带型，是轻度染色体异常，如平衡易位、倒位[46，XY，t(5，12)]等，遗传信息并不少，只是染色体片段发生位移，这样的人外表和生殖腺正常，也不会导致流产，充其量出生的后代染色体与上代一样而已。正所谓龙生龙，凤生凤，老鼠生来会打洞。

In fact, couples with chromosomal abnormalities do not lead to habitual miscarriage. The reason is that chromosomal abnormalities are formed at the beginning of sperm egg binding. There are three kinds of chromosomal abnormalities: fatal abnormalities; Disabling abnormalities; Portable anomaly. The lethal type is a serious chromosome variation. The outcome is that the embryo withers and naturally miscarries, and there will be no baby born. The disability type is a moderately abnormal chromosome, and it is mostly a change in the number of chromosomes. For example, 21 trisomes, 22 trisomes, Turner syndrome(more than one Y chromosome), etc., are all born with disabilities and are basically infertile. Portable type, is a mild chromosomal anomaly, such as equilibrium transposition, inversion[ 46, XY, T(5, 12)] And so on, there is a lot of genetic information, but the chromosomal fragments are displaced. Such a person's appearance and gonad are normal, and it will not lead to miscarriage. At best, the offspring born have the same chromosomes as the previous generation. The so-called dragon born Dragon, Phoenix born Phoenix, mice born to make holes.