染色体疾病多见吗?Are chromosomal diseases common?

陈凤林教授指出：染色体是遗传物质的载体，是脱氧核糖核酸(DNA)以及核蛋白在细胞分裂时的呈现形式。正常人的体细胞染色体数目为46条，并有一定的形态和结构。染色体在形态结构或数量上的异常被成为染色体异常，由染色体异常引起的疾病为染色体病。

Professor Chen Fenglin pointed out that chromosomes are the carriers of genetic material and the presentation forms of deoxyribonucleic acid (DNA) and nucleoprotein during cell division. The number of somatic chromosomes in normal human is 46, and it has certain morphology and structure. Chromosome abnormalities in morphology or number are called chromosome abnormalities, and diseases caused by chromosome abnormalities are chromosome diseases.

现已发现的染色体病有100余种，染色体病在临床上常可造成流产、先天愚型、先天性多发性畸形、以及癌肿等。染色体异常的发生率并不少见，在一般新生儿群体中就可达0.5%-0.7%。

More than 100 kinds of chromosomal diseases have been found. Chromosomal diseases often cause miscarriage, congenital foolish type, congenital multiple malformations, and cancer in clinic. The incidence of chromosomal abnormalities is not uncommon, which can reach 0.5% - 0.7% in the general neonatal population.