夫妇染色体异常会不会导致习惯性流产胎停育?Can couples'chromosomal abnormalities lead to habitual miscarriage and fetal growth cessation?

陈凤林教授指出：夫妇染色体异常不会导致习惯性流产。原因是，染色体异常形成于精卵结合之初，染色体异常有三种情况：致死型异常;致残型异常;携带型异常。Professor Chen Fenglin pointed out that couples with chromosomal abnormalities would not lead to habitual miscarriage. The reason is that chromosome abnormalities are formed at the beginning of sperm-egg binding. There are three kinds of chromosome abnormalities: lethal abnormalities, disabled abnormalities and carrier abnormalities.

致死型，是染色体严重变异，如多倍体，单倍体等，结局是在细胞分化阶段即停止发育，也就是所谓的生化妊娠，不会有胚胎的形成。 致残型，是染色体中度异常，多是染色体数量变化，如21三体，22三体，特纳综合征(多一条Y染色体)，克氏综合征(多一条X染色体)，出生的都是残疾人，基本都无生育能力。The lethal type is a serious variation of chromosome, such as polyploid, haploid, etc. The result is that the development of cells stops at the stage of cell differentiation, that is, so-called biochemical pregnancy, there will be no embryo formation. Disabled type is a moderate chromosome abnormality. Most of them are chromosome number changes, such as trisomy 21, trisomy 22, Turner syndrome (more than one Y chromosome), Kerr's syndrome (more than one X chromosome). All of them are born with disabilities and are basically sterile.

携带型，是轻度染色体异常，如平衡易位、倒位[46，XY，t(5，12)]等，遗传信息并不少，只是染色体片段发生位移，这样的人外表和生殖腺正常，也不会导致流产，充其量出生的后代染色体与上代一样而已。正所谓龙生龙，凤生凤，老鼠生来会打洞。Carrier type is a mild chromosomal abnormality, such as balanced translocation, inversion [46, XY, t (5, 12)]. There is a lot of genetic information, but the chromosome fragments have been displaced. Such a person has normal appearance and reproductive glands, and will not cause miscarriage. At best, the offspring born in quantity have the same chromosome as the previous generation. The so-called dragon born dragon, phoenix born phoenix, mice born to hole.